What is the recommended duration of post-exposure prophylaxis (PEP) after exposure?

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Multiple Choice

What is the recommended duration of post-exposure prophylaxis (PEP) after exposure?

Explanation:
Post-exposure prophylaxis after potential HIV exposure uses antiretroviral therapy started promptly to block viral replication if infection has occurred. The recommended duration is 28 days (four weeks). Completing the full 28-day course provides adequate coverage during the early window when the virus can establish infection, giving the best chance to prevent seroconversion. Shorter courses, like 7 or 14 days, are not sufficient to guarantee protection and are not the standard approach. A much longer course, such as 60 days, does not increase effectiveness and raises the risk of adverse effects. For maximum effectiveness, start PEP as soon as possible, ideally within 72 hours of exposure.

Post-exposure prophylaxis after potential HIV exposure uses antiretroviral therapy started promptly to block viral replication if infection has occurred. The recommended duration is 28 days (four weeks). Completing the full 28-day course provides adequate coverage during the early window when the virus can establish infection, giving the best chance to prevent seroconversion. Shorter courses, like 7 or 14 days, are not sufficient to guarantee protection and are not the standard approach. A much longer course, such as 60 days, does not increase effectiveness and raises the risk of adverse effects. For maximum effectiveness, start PEP as soon as possible, ideally within 72 hours of exposure.

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